What is the Endocannabinoid System

Saturday, October 26th, 2019

The endocannabinoid system, or ECS, was first discovered in the early and mid-’90s by Mechoulam and colleagues when they located and identified two of the body’s naturally produced major endocannabinoids, discovering the presence of the endocannabinoid system.  The ECS is a key homeostatic regulator in the body, playing a role in almost every physiological system in the body. The ECS does this via cannabinoid receptors found in select tissues. We have (at least) two types of cannabinoid receptors:

  • CB1 which is in the central nervous system (brain and nerves of the spinal cord)
  • CB2 which is in the peripheral nervous system (nerves in your extremities), the digestive system, and specialized cells in the immune system


Through those receptors, the ECS helps regulate a lot of important functions, such as:

  • Appetite
  • Digestion
  • Immune function
  • Inflammation, including neuroinflammation
  • Mood
  • Sleep
  • Reproduction/fertility
  • Motor control
  • Temperature regulation
  • Memory
  • Pain
  • Pleasure/reward


Your body activates the ECS with precision so that it impacts only what it needs to. For example, if your reproductive hormones are out of whack, it will work to regulate them without altering your digestion or immune system.


Learning how to supplement our ECS with CBD has been a game-changer in how we contribute to our health. By assisting our ECS to perform optimally, we are able to help so many physiological systems in our body perform optimally, improving our overall health.